Free MPJE Practice Test: 50 Questions With Explanations

Fifty original practice questions: 39 on federal pharmacy law that state-specific MPJEs can test, plus 11 jurisdiction-rule drills that practice applying a state rule the question gives you. Answer under federal law unless a question supplies a state rule. Taking the Uniform MPJE instead? Use the free UMPJE practice questions. Not sure your jurisdiction still uses the MPJE? Check which law exam applies.

50 questions · one-answer and select-all formats · about 63 minutes at real exam pace · no sign-up · original Castleport questions, not NABP items or recalled exam content · last verified September 25, 2026

Practice questions

Federal questions assume no stricter state rule applies unless the question says otherwise. Select-all questions can have two, three, or four correct choices. Reveal each answer only after you commit.

Question 1 of 50

Area 3: Dispensing Requirements · Choose one

A pharmacy receives an electronic prescription for oxycodone 5 mg tablets, #60, written on September 1, 2026. On September 3, the patient asks the pharmacist to dispense only 20 tablets now and hold the rest. State law does not prohibit partial filling, and the pharmacy has enough stock. Under federal law, what is the last date any remaining tablets may be dispensed on this prescription?

A. September 6, 2026
B. October 1, 2026
C. October 3, 2026
D. October 31, 2026
E. No deadline applies as long as the total dispensed does not exceed 60 tablets

Reveal answer and explanation

Answer: B. October 1, 2026
A partial fill the patient asks for follows the patient-request rule: any remaining portion must be filled no later than 30 days after the date the prescription was written. September 1 plus 30 days is October 1. September 6 applies the 72-hour rule, which is for a pharmacy that can't supply the full quantity. October 3 counts from the first fill instead of the written date. October 31 borrows the 60-day window for long-term care or terminally ill patients. The pharmacist also records that the patient requested the partial fill, the date of the request, and the quantity dispensed.
Source: 21 CFR 1306.13(b)(2) and (b)(5)(ii)
Check your state: Federal law allows patient-requested Schedule II partial fills only where state law doesn't prohibit them (1306.13(b)(1)(i)). Look up your state's rule.

Show all 50 answers in the complete self-scoring key

By the Castleport Test Prep Editorial Team

Question 2 of 50

Area 2: Pharmacist Practice · Choose one

A prescriber wants a stable ADHD patient to receive three months of a Schedule II stimulant without writing a new prescription each month. Assume no stricter state rule applies. Which approach does federal law permit?

A. Three separate prescriptions issued the same day, each after the first showing the earliest date it may be filled, for a combined total of no more than a 90-day supply
B. One prescription that the pharmacy partially fills every 30 days for 90 days at the patient's request
C. One prescription that the patient transfers to a new pharmacy each month
D. One prescription marked "refills × 2"
E. One prescription, plus a phoned-in refill authorization each month

Reveal answer and explanation

Answer: A. Three separate prescriptions issued the same day, each after the first showing the earliest date it may be filled, for a combined total of no more than a 90-day supply
Schedule II prescriptions can't be refilled, so any "refill" route fails. Federal law instead lets a prescriber issue multiple Schedule II prescriptions totaling up to a 90-day supply, with the earliest fill date written on each prescription after the first. The monthly partial-fill idea fails because remaining portions of a patient-requested partial must be filled within 30 days of the date written. Transfers don't create new quantity.
Source: 21 CFR 1306.12(a) and (b)(1); 21 CFR 1306.13(b)(2)
Check your state: The multiple-prescription approach must be permissible under your state's law (1306.12(b)(1)(iv)). Look up your state's rule.

Question 3 of 50

Area 4: Pharmacy Operations · Choose one

A chain pharmacy owned by a corporation wants its new store manager, who is not a corporate officer, to sign DEA Form 222 orders. Who must sign a valid power of attorney granting that authority?

A. The store manager alone, with the document notarized
B. A corporate officer, the store manager being appointed, and two witnesses
C. The pharmacist-in-charge alone
D. The person who signed the store's most recent DEA registration application
E. The local DEA Diversion Field Office

Reveal answer and explanation

Answer: B. A corporate officer, the store manager being appointed, and two witnesses
A power of attorney for Form 222s must be signed by the registrant (for a corporation, an officer), by the person receiving the authority, and by two witnesses. The pharmacist-in-charge isn't automatically an officer. DEA's March 20, 2026 technical amendments removed leftover wording that tied Form 222 signing authority and power-of-attorney revocation to whoever signed the last registration application, so that option is a trap. DEA doesn't sign a registrant's power of attorney, and notarization isn't the requirement.
Source: 21 CFR 1305.05(d); DEA Diversion Control Division, DEA Form 222 Q&A (power of attorney answer); Federal Register, March 20, 2026: DEA Form 222 technical amendments (amendments to 1305.05(e) and 1305.12(d))

Question 4 of 50

Area 1: Licensure/Personnel · Choose one

A pharmacy wants to hire a technician who, several years ago, surrendered a DEA registration in lieu of disciplinary action over the handling of controlled substances. Under federal DEA rules, may this person be employed with access to controlled substances?

A. No
B. Yes, but only for Schedule III through V drugs
C. Yes, if the person holds an active state technician license
D. Yes, if a pharmacist directly supervises every task
E. Yes, once five years have passed since the surrender

Reveal answer and explanation

Answer: A. No
A registrant may not employ anyone with access to controlled substances who surrendered a DEA registration "for cause." The regulation defines for cause as a surrender in lieu of, or because of, an administrative, civil, or criminal action from an investigation of the person's handling of controlled substances. That's this fact pattern. The rule has no exception for supervision, schedule, a state license, or time passed.
Source: 21 CFR 1301.76(a)
Check your state: Look up any added background or registration rules your board applies to technicians.

Question 5 of 50

Area 2: Pharmacist Practice · Choose one

A pharmacist dispensed a Schedule II drug on a prescriber's emergency oral authorization. Eight days later, the follow-up written prescription still hasn't arrived and wasn't mailed. What must the pharmacist do under federal law?

A. Ask the patient to return any unused tablets
B. Convert the record to a partial fill
C. Nothing further; the dispensing is complete
D. Notify the nearest DEA office
E. Wait up to 30 days for the prescription to arrive

Reveal answer and explanation

Answer: D. Notify the nearest DEA office
The prescriber must deliver a written prescription for the emergency quantity within 7 days (a mailed one must be postmarked within the 7 days). If it doesn't come, the pharmacist must notify the nearest DEA office. If the pharmacist fails to notify, the authority to dispense without a written prescription is void. Waiting longer, relabeling the fill, or recovering tablets doesn't satisfy the rule.
Source: 21 CFR 1306.11(d)(4)

Question 6 of 50

Area 3: Dispensing Requirements · Select all that apply

When dispensed to a patient, which of these must carry the label statement "Caution: Federal law prohibits the transfer of this drug to any person other than the patient for whom it was prescribed"? (Select ALL that apply.)

A. A Schedule II drug
B. A Schedule III drug
C. A Schedule IV drug
D. A Schedule V drug
E. A noncontrolled prescription drug

Reveal answer and explanation

Answers: A. A Schedule II drug; B. A Schedule III drug; C. A Schedule IV drug
The federal regulation requires the transfer warning on dispensed Schedule II, III, and IV drugs. Schedule V isn't listed, so the federal rule doesn't require the warning there. Noncontrolled drugs aren't covered. The only exception written into the rule is for controlled substances dispensed in blind clinical investigations.
Source: 21 CFR 290.5
Check your state: Look up your state's prescription label requirements, which apply alongside this one.

Question 7 of 50

Area 4: Pharmacy Operations · Choose one

On Monday, October 5, 2026, a pharmacist discovers that Schedule II tablets were stolen. Which timeline meets the federal reporting requirements?

A. Written notice to the DEA Field Division Office by Tuesday, October 6, and a DEA Form 106 filed electronically by November 19, 2026
B. A report only if the amount stolen is "significant"
C. A DEA Form 41 filed within 7 days
D. A phone call to DEA the same day; no form is needed if the call is made
E. A DEA Form 106 mailed on paper within 45 days; no earlier notice is needed

Reveal answer and explanation

Answer: A. Written notice to the DEA Field Division Office by Tuesday, October 6, and a DEA Form 106 filed electronically by November 19, 2026
Two steps. First, written notice to the DEA Field Division Office within one business day of discovery (a phone call isn't written notice). Second, a complete and accurate DEA Form 106 filed through DEA's secure online application within 45 days after discovery: October 5 plus 45 days is November 19. Form 41 is for destruction, not theft. The "significant" test applies to losses; a theft is reported regardless.
Source: 21 CFR 1301.76(b)

Question 8 of 50

Jurisdiction-rule drill · Area 1: Licensure/Personnel · Choose one

Jurisdiction rule (assume for this question): Each pharmacist on duty may supervise no more than 3 pharmacy technicians performing technician functions. Two pharmacists are on duty and 7 technicians are scheduled. How many technicians may perform technician functions at the same time?

A. 3
B. 4
C. 6
D. 7
E. 8

Reveal answer and explanation

Answer: C. 6
Two pharmacists × 3 technicians each = 6. The seventh technician can't perform technician functions until another pharmacist is on duty or a technician steps away from those duties. Ratio questions reward doing the arithmetic from the rule exactly as written, not from how a store usually staffs.
Drill basis: NABP MPJE Competency Statements, Area 1, statement 1.1
Check your state: On your real MPJE, use your board's actual technician-ratio rule.

Question 9 of 50

Area 2: Pharmacist Practice · Select all that apply

Under federal DEA rules, which must appear on a controlled-substance prescription? (Select ALL that apply.)

A. The practitioner's name, address, and DEA registration number
B. The patient's full name and address
C. The date issued, with the prescription signed on that same day
D. The patient's date of birth
E. The drug name, strength, dosage form, quantity prescribed, and directions for use

Reveal answer and explanation

Answers: A. The practitioner's name, address, and DEA registration number; B. The patient's full name and address; C. The date issued, with the prescription signed on that same day; E. The drug name, strength, dosage form, quantity prescribed, and directions for use
Federal rules require a controlled-substance prescription to be dated as of, and signed on, the day issued, and to show the patient's full name and address; the drug name, strength, dosage form, quantity, and directions; and the practitioner's name, address, and registration number. Date of birth isn't a federal element. One related detail: a prescription for gamma-hydroxybutyric acid must also note the patient's medical need.
Source: 21 CFR 1306.05(a) and (c)
Check your state: Look up whether your state requires additional prescription elements.

Question 10 of 50

Area 3: Dispensing Requirements · Choose one

A Schedule IV prescription with 3 refills left was transferred from Pharmacy A to Pharmacy B last month. The patient now asks Pharmacy B to transfer it to Pharmacy C. The pharmacies do not share a real-time, online database. Under federal law, what happens?

A. The prescription can't be transferred again; the patient needs a new prescription at Pharmacy C
B. Pharmacy B transfers it if B and C have the same owner
C. Pharmacy B transfers it because refills remain
D. Pharmacy B transfers it because the prescription is less than six months old
E. Pharmacy B may transfer it once per calendar year

Reveal answer and explanation

Answer: A. The prescription can't be transferred again; the patient needs a new prescription at Pharmacy C
Transfers of Schedule III–V prescription information for refills are allowed on a one-time basis only. The exception is for pharmacies electronically sharing a real-time, online database, which may transfer up to the maximum refills allowed by law and the prescriber. The stem rules that out, and common ownership alone isn't the exception.
Source: 21 CFR 1306.25(a)
Check your state: Look up whether your state adds limits on controlled-substance transfers.

Question 11 of 50

Area 4: Pharmacy Operations · Select all that apply

During the biennial inventory, which opened containers require an exact count or measure under federal rules? (Select ALL that apply.)

A. An opened Schedule IV bottle that held 900 tablets when full
B. An opened bottle of Schedule V tablets that holds 90 tablets
C. An opened bottle of Schedule III tablets that holds 300 tablets
D. An opened Schedule IV bottle that held 1,200 tablets when full
E. An opened bottle of Schedule II tablets

Reveal answer and explanation

Answers: D. An opened Schedule IV bottle that held 1,200 tablets when full; E. An opened bottle of Schedule II tablets
For opened containers, Schedule I and II need an exact count or measure. Schedule III–V may be estimated unless the container holds more than 1,000 tablets or capsules, so the 1,200-count Schedule IV bottle needs an exact count and the 900-count one doesn't. The 300-count Schedule III and 90-count Schedule V bottles may be estimated.
Source: 21 CFR 1304.11(e)(6)

Question 12 of 50

Jurisdiction-rule drill · Area 2: Pharmacist Practice · Choose one

Jurisdiction rule (assume for this question): Pharmacists may administer vaccines under protocol to patients 7 years and older; younger patients require a prescription. A parent brings in a 6-year-old for a vaccine that is on the pharmacy's protocol. There is no prescription. What should the pharmacist do?

A. Administer it if the child turns 7 this month
B. Not administer it under protocol; a prescription is required
C. Administer it because the vaccine is on the protocol
D. Administer it and notify the child's pediatrician afterward
E. Administer it under protocol with the parent's written consent

Reveal answer and explanation

Answer: B. Not administer it under protocol; a prescription is required
The supplied rule makes age the gate. A 6-year-old is below it, so protocol authority doesn't apply no matter who consents or what the protocol lists. "Turns 7 this month" is still 6 today.
Drill basis: NABP MPJE Competency Statements, Area 2, statement 2.2
Check your state: On your real MPJE, use your state's pharmacist immunization authority and age limits.

Question 13 of 50

Area 1: Licensure/Personnel · Choose one

A state permits nonprescription sale of certain Schedule V products. Under federal rules, which part of such a sale may a nonpharmacist employee handle?

A. Deciding whether the sale may be made
B. Checking the purchaser's ID and making the sale while a pharmacist supervises
C. Making the record-book entry on the pharmacist's behalf
D. Making the sale without the pharmacist if the purchaser is a regular customer
E. Completing the cash register transaction after the pharmacist has fulfilled the dispensing and recordkeeping duties

Reveal answer and explanation

Answer: E. Completing the cash register transaction after the pharmacist has fulfilled the dispensing and recordkeeping duties
Only a pharmacist may dispense a controlled substance without a prescription, and the regulation says that isn't satisfied by a nonpharmacist employee even under supervision. After the pharmacist has met the professional and legal duties, a nonpharmacist may complete the cash, credit, or delivery part of the transaction.
Source: 21 CFR 1306.26(a)
Check your state: Look up whether your state allows nonprescription Schedule V sales at all.

Question 14 of 50

Area 3: Dispensing Requirements · Choose one

At 9 a.m., a customer buys products containing 2.4 g of pseudoephedrine base. At 4 p.m. the same day, the customer returns and asks for another 2.4 g of base. Under federal law, what is the most additional pseudoephedrine base the pharmacy may sell this customer today?

A. 0 g
B. 1.2 g
C. 2.4 g
D. 3.6 g
E. 7.5 g

Reveal answer and explanation

Answer: B. 1.2 g
A regulated seller may not sell one purchaser more than 3.6 g of pseudoephedrine base in a single calendar day, regardless of the number of transactions. 3.6 − 2.4 = 1.2 g. The limit counts base, not the salt weight printed on many packages. 7.5 g is a 30-day figure for mobile retail vendors and mail-order sellers, not a daily pharmacy limit.
Source: 21 CFR part 1314, subpart B (daily sales limit); 21 U.S.C. 830(d)
Check your state: Look up whether your state sets lower limits or requires a prescription.

Question 15 of 50

Area 2: Pharmacist Practice · Choose one

A Schedule IV prescription was issued on March 2, 2026, and still has 2 refills left. The patient asks for a refill on September 8, 2026. Under federal law, what is the result?

A. Refill it because refills remain
B. Refill it if the prescriber phones in approval
C. Don't refill it; a new prescription is needed
D. Refill up to a 30-day supply only
E. Refill it once more, then require a new prescription

Reveal answer and explanation

Answer: C. Don't refill it; a new prescription is needed
Schedule III and IV prescriptions can't be filled or refilled more than six months after the date issued. Six months from March 2 is September 2, so the September 8 request is too late even with refills left. A prescriber's oral authorization can add refills only within the same five-refill, six-month limits, so a phone call can't revive it.
Source: 21 CFR 1306.22(a) and (e)(1)

Question 16 of 50

Area 4: Pharmacy Operations · Choose one

What is the minimum federal retention period for a pharmacy's controlled-substance inventories and required records?

A. At least 2 years from the date of the inventory or record
B. 5 years
C. Until the next DEA inspection
D. 3 years
E. 1 year

Reveal answer and explanation

Answer: A. At least 2 years from the date of the inventory or record
Federal rules require every required inventory and record to be kept and available for DEA inspection and copying for at least 2 years from the date of the inventory or record.
Source: 21 CFR 1304.04(a)
Check your state: The federal period is a minimum. Look up your state's retention period.

Question 17 of 50

Jurisdiction-rule drill · Area 1: Licensure/Personnel · Choose one

Jurisdiction rule (assume for this question): Pharmacists must complete 30 hours of continuing education per two-year renewal, including at least 2 hours in pharmacy law. Pharmacists first licensed by examination are exempt at their first renewal. A pharmacist licensed by examination is now completing the second renewal. What is required?

A. 15 hours, prorated for the first license period
B. 30 hours, with no law requirement
C. 30 hours, including at least 2 hours in pharmacy law
D. 2 hours in pharmacy law only
E. No hours, because of the first-renewal exemption

Reveal answer and explanation

Answer: C. 30 hours, including at least 2 hours in pharmacy law
The exemption covers the first renewal only. At the second renewal, the full rule applies: 30 hours including at least 2 in pharmacy law. Proration isn't in the supplied rule.
Drill basis: NABP MPJE Competency Statements, Area 1, statement 1.2
Check your state: On your real MPJE, use your board's actual CE hours, topic requirements, and first-renewal rule.

Question 18 of 50

Area 2: Pharmacist Practice · Choose one

A prescriber's agent faxes a Schedule II narcotic prescription for a patient enrolled in a state-licensed hospice program and notes "hospice patient" on it. May the fax serve as the original written prescription?

A. Only if the patient lives in a long-term care facility
B. Only if the prescriber signs the fax a second time
C. No; the original signed prescription must be presented before dispensing
D. Yes
E. Only for a 72-hour supply

Reveal answer and explanation

Answer: D. Yes
The general rule is that a faxed Schedule II prescription needs the original manually signed prescription presented before dispensing. There's a listed exception: a Schedule II narcotic prescription for a patient in a Medicare-certified or state-licensed hospice, with the hospice status noted, may be faxed and the fax serves as the original.
Source: 21 CFR 1306.11(a) and (g)

Question 19 of 50

Area 3: Dispensing Requirements · Choose one

A pharmacy can supply only 10 of 30 tablets on a Schedule II prescription. The patient isn't in long-term care, isn't terminally ill, and didn't request a partial fill. The remaining 20 tablets don't arrive within 72 hours. What does federal law require?

A. Transfer the remainder to another pharmacy
B. Treat the remainder as an emergency oral prescription
C. Supply the remainder any time within 60 days
D. Notify the prescriber; no further quantity may be supplied without a new prescription
E. Supply the remainder any time within 30 days

Reveal answer and explanation

Answer: D. Notify the prescriber; no further quantity may be supplied without a new prescription
When the pharmacy can't supply the full quantity, the remainder may be filled within 72 hours of the first partial fill. If it isn't, the pharmacist must notify the prescriber, and nothing more may be dispensed beyond 72 hours without a new prescription. The 30-day and 60-day windows belong to other partial-fill pathways.
Source: 21 CFR 1306.13(a)

Question 20 of 50

Area 4: Pharmacy Operations · Choose one

DEA adds a drug the pharmacy stocks to Schedule IV. It was not previously controlled. When must the pharmacy inventory it?

A. Within 30 days of the rule's effective date
B. On the effective date of the scheduling rule, and in every biennial inventory after that
C. Never, for stock purchased before scheduling
D. At the next biennial inventory only
E. Only if the pharmacy has more than 1,000 units

Reveal answer and explanation

Answer: B. On the effective date of the scheduling rule, and in every biennial inventory after that
When DEA adds a substance that wasn't previously scheduled, every registrant that has it must inventory all stock on hand on the effective date of the rule. After that, it's included in each biennial inventory.
Source: 21 CFR 1304.11(d)

Question 21 of 50

Area 2: Pharmacist Practice · Choose one

A Medicaid patient declines the pharmacist's offer to counsel on a new prescription. Under the federal Medicaid drug-review standards, what follows?

A. The prescription can't be dispensed
B. The pharmacist must report the refusal to CMS
C. Counseling need not be provided, and the refusal is documented as the state's standards require
D. The offer to counsel wasn't required for a Medicaid patient
E. The pharmacist must counsel anyway

Reveal answer and explanation

Answer: C. Counseling need not be provided, and the refusal is documented as the state's standards require
The federal Medicaid rules require state standards that make pharmacists offer to counsel each beneficiary who presents a prescription. The standards need not require counseling when the beneficiary refuses, and they must specify what documentation of the refusal is required.
Source: 42 CFR 456.705(c)(2)(i)–(iii)
Check your state: Look up your state's counseling rules, including new versus refill prescriptions and how refusals are documented.

Question 22 of 50

Area 1: Licensure/Personnel · Select all that apply

Under federal DEA rules, which histories bar a pharmacy from employing a person with access to controlled substances? (Select ALL that apply.)

A. A felony conviction for tax fraud
B. A felony conviction relating to controlled substances
C. A DEA registration surrendered for cause
D. A denied application for DEA registration
E. A state technician license that lapsed for nonpayment

Reveal answer and explanation

Answers: B. A felony conviction relating to controlled substances; C. A DEA registration surrendered for cause; D. A denied application for DEA registration
The federal bar covers a felony conviction relating to controlled substances, a denied DEA registration application, a revoked registration, and a registration surrendered for cause. A felony unrelated to controlled substances isn't on the federal list, and neither is a license lapse for nonpayment, though a state or employer rule may reach them.
Source: 21 CFR 1301.76(a)
Check your state: Look up your board's technician registration and background rules.

Question 23 of 50

Area 3: Dispensing Requirements · Select all that apply

Which screenings are required elements of prospective drug review under the federal Medicaid rules? (Select ALL that apply.)

A. Incorrect duration of drug treatment
B. Therapeutic duplication
C. Verification of the prescriber's license status
D. Drug-allergy interactions
E. Comparison with the lowest-cost generic

Reveal answer and explanation

Answers: A. Incorrect duration of drug treatment; B. Therapeutic duplication; D. Drug-allergy interactions
Prospective review must screen for therapeutic duplication, drug-disease contraindications, drug-drug interactions, incorrect dosage, incorrect duration, drug-allergy interactions, and clinical abuse or misuse. Cost comparison and license checks aren't on that list.
Source: 42 CFR 456.705(b)(1)–(7)
Check your state: Look up your state's prospective drug review and prescription monitoring program (PDMP) rules.

Question 24 of 50

Area 2: Pharmacist Practice · Choose one

A Schedule IV prescription issued three months ago authorized 2 refills, and both have been used. The prescriber phones the pharmacist to authorize 3 more refills, each the same quantity as the original fill. Under federal law, what is the result?

A. Not allowed; a new prescription is required
B. Allowed only if each added refill is smaller than the original
C. Allowed only if the authorization arrives in writing
D. Allowed, and the pharmacist records the date, quantity, number of added refills, and who received the authorization
E. Allowed, and the prescriber may add 4 refills instead of 3

Reveal answer and explanation

Answer: D. Allowed, and the pharmacist records the date, quantity, number of added refills, and who received the authorization
A prescriber may add Schedule III or IV refills to the original prescription by oral authorization if the total stays within five refills and six months from issue, and each added refill is no larger than the original quantity. Two used plus three added is five, and the prescription is only three months old. Adding 4 would make six refills, over the limit.
Source: 21 CFR 1306.22(e)(1)–(3)

Question 25 of 50

Area 4: Pharmacy Operations · Select all that apply

Which storage methods for Schedule II–V drugs in a retail pharmacy meet the federal security rule? (Select ALL that apply.)

A. Dispersal throughout the noncontrolled stock in a way that obstructs theft
B. Schedule II in a locked cabinet, with Schedule III–V dispersed
C. A designated open shelf behind the counter
D. A securely locked, substantially constructed cabinet
E. An unlocked box kept out of public view

Reveal answer and explanation

Answers: A. Dispersal throughout the noncontrolled stock in a way that obstructs theft; B. Schedule II in a locked cabinet, with Schedule III–V dispersed; D. A securely locked, substantially constructed cabinet
Federal rules require Schedule II–V drugs to be stored in a securely locked, substantially constructed cabinet, but let pharmacies instead disperse them throughout the noncontrolled stock to obstruct theft or diversion. Mixing the two methods satisfies the rule. Hiding drugs in an unlocked box or grouping them on an open shelf does neither.
Source: 21 CFR 1301.75(b)
Check your state: Look up whether your state requires Schedule II drugs to be locked rather than dispersed.

Question 26 of 50

Jurisdiction-rule drill · Area 1: Licensure/Personnel · Choose one

Jurisdiction rule (assume for this question): When the pharmacist-in-charge changes, the owner must notify the board in writing within 10 days, and the incoming pharmacist-in-charge must complete a controlled-substance inventory on the date they assume the position. What must happen on the new PIC's first day?

A. The outgoing PIC completes an inventory within 10 days
B. A DEA Form 106 is filed
C. The incoming PIC completes a controlled-substance inventory
D. The owner's written notice to the board
E. Nothing until the board approves the change

Reveal answer and explanation

Answer: C. The incoming PIC completes a controlled-substance inventory
The supplied rule sets two deadlines. The inventory is due on the first day; the owner's notice has 10 days. Nothing in the rule waits on board approval, and Form 106 is a theft-or-loss report.
Drill basis: NABP MPJE Competency Statements, Area 1, statement 1.1
Check your state: On your real MPJE, use your state's PIC-change notice and inventory rule.

Question 27 of 50

Area 3: Dispensing Requirements · Choose one

Pharmacy A is out of stock on an unfilled electronic Schedule II prescription. The patient asks Pharmacy A to send it to Pharmacy B. Both are retail pharmacies. Under federal law, what is allowed?

A. Nothing; Schedule II prescriptions can never be transferred
B. Transfer only if the drug is in Schedule III–V
C. A one-time transfer in electronic form, if state law allows it
D. Transfers back and forth until one pharmacy fills it
E. Pharmacy A may print the prescription and fax it to Pharmacy B

Reveal answer and explanation

Answer: C. A one-time transfer in electronic form, if state law allows it
DEA's 2023 rule allows an electronic prescription for a Schedule II–V drug to be transferred between retail pharmacies for initial dispensing, one time, in its electronic form, and only where state or other applicable law allows it. Printing and faxing breaks the electronic-form requirement.
Source: 21 CFR 1306.08(f)–(g); Federal Register, July 27, 2023: transfer of electronic Schedule II–V prescriptions for initial filling (final rule summary)
Check your state: This transfer is permitted only where state law allows it. Look up your state's rule.

Question 28 of 50

Area 2: Pharmacist Practice · Choose one

A patient picks up the fourth refill of a prescription drug that requires an FDA-approved Medication Guide. What does federal law require?

A. Provide it only when the guide's content changes
B. Provide it only if the patient asks
C. Provide the Medication Guide directly to the patient with this refill, unless an exemption applies
D. Provide it only to new patients
E. Provide the Medication Guide only on the first fill

Reveal answer and explanation

Answer: C. Provide the Medication Guide directly to the patient with this refill, unless an exemption applies
Each authorized dispenser must provide the Medication Guide directly to the patient or the patient's agent when the product is dispensed, unless an exemption under 21 CFR 208.26 applies. A refill is a dispensing.
Source: 21 CFR 208.24(e)

Question 29 of 50

Area 4: Pharmacy Operations · Choose one

A pharmacy took its last biennial inventory at the close of business on May 4, 2025. Which statement about the next one is correct under federal rules?

A. It must be taken within one year
B. It may be taken on any date on or before May 4, 2027, at opening or close of business, with the choice noted on the inventory
C. It must again be taken at close of business
D. It must be taken on May 4, 2027 exactly
E. Only Schedule II drugs need to be inventoried

Reveal answer and explanation

Answer: B. It may be taken on any date on or before May 4, 2027, at opening or close of business, with the choice noted on the inventory
A biennial inventory may be taken on any date within two years of the previous one. It may be taken as of the opening or the close of business, and the inventory must say which. It covers all controlled substances on hand, not just Schedule II.
Source: 21 CFR 1304.11(a) and (c)
Check your state: Look up whether your state requires more frequent inventories or inventories at events such as a PIC change.

Question 30 of 50

Jurisdiction-rule drill · Area 2: Pharmacist Practice · Choose one

Jurisdiction rule (assume for this question): A drug that has been dispensed and taken out of the pharmacy may not be returned to stock. A filled prescription that was never picked up may be returned to stock if it stays in its original labeled container and a pharmacist verifies it. Which item may go back to stock?

A. A sealed bottle a patient brings back from home
B. An unopened bottle returned by the patient's caregiver
C. Any product with at least 12 months until expiration
D. A delivery the patient refused at the door after it left the store
E. A filled prescription that sat in will-call and was never picked up

Reveal answer and explanation

Answer: E. A filled prescription that sat in will-call and was never picked up
The supplied rule turns on whether the drug left the pharmacy. Items back from home, from a caregiver, or from a delivery driver all left the pharmacy. Only the never-picked-up will-call prescription stayed under the pharmacy's control. Expiration dating isn't part of the rule.
Drill basis: NABP MPJE Competency Statements, Area 2, statement 2.4
Check your state: On your real MPJE, use your state's return and reuse rule, including any exceptions for institutional unit-dose returns.

Question 31 of 50

Area 1: Licensure/Personnel · Choose one

A pharmacy sells nonprescription products containing pseudoephedrine. Under federal law, what applies to employees who hand these products to customers or take their payments?

A. The seller must self-certify to DEA that these employees have been trained on the sales requirements
B. Each employee must hold a DEA registration
C. No federal training requirement applies
D. Only pharmacists may ring up the sale
E. Employees must be at least 21

Reveal answer and explanation

Answer: A. The seller must self-certify to DEA that these employees have been trained on the sales requirements
The Combat Methamphetamine Epidemic Act requires a regulated seller to submit a self-certification that the individuals who deliver these products or take payment have been trained on the federal sales requirements. It doesn't require employees to be registered or pharmacists.
Source: 21 U.S.C. 830(e)(1)(A)(vii); DEA Diversion Control Division, CMEA general information (self-certification and training)

Question 32 of 50

Area 3: Dispensing Requirements · Select all that apply

A Schedule II prescription is written for a resident of a long-term care facility. Which statements are correct under federal law? (Select ALL that apply.)

A. The pharmacist records "LTCF patient" on the prescription
B. It may be partially filled, including in individual dosage units
C. The total dispensed may exceed the prescribed quantity if the prescriber calls
D. Each remaining portion must be filled within 72 hours
E. It stays valid for no more than 60 days from the issue date, unless the medication is discontinued sooner

Reveal answer and explanation

Answers: A. The pharmacist records "LTCF patient" on the prescription; B. It may be partially filled, including in individual dosage units; E. It stays valid for no more than 60 days from the issue date, unless the medication is discontinued sooner
Schedule II prescriptions for LTCF or terminally ill patients may be partially filled, including individual dosage units. The pharmacist must record "LTCF patient" or "terminally ill," and the prescription is valid for no more than 60 days from issue. The 72-hour limit belongs to the pharmacy-can't-supply pathway. The total can never exceed the quantity prescribed.
Source: 21 CFR 1306.13(c)

Question 33 of 50

Area 2: Pharmacist Practice · Select all that apply

Which are federal requirements when a pharmacist dispenses a Schedule II drug on a prescriber's emergency oral authorization? (Select ALL that apply.)

A. The prescriber delivers a written prescription within 7 days, marked "Authorization for Emergency Dispensing" with the date of the oral order
B. The pharmacist may dispense up to a 30-day supply
C. The quantity is limited to the amount needed during the emergency period
D. The pharmacist immediately reduces the authorization to writing
E. The prescriber's follow-up is due within 72 hours

Reveal answer and explanation

Answers: A. The prescriber delivers a written prescription within 7 days, marked "Authorization for Emergency Dispensing" with the date of the oral order; C. The quantity is limited to the amount needed during the emergency period; D. The pharmacist immediately reduces the authorization to writing
The emergency pathway is narrow: the amount must be adequate only for the emergency period, the pharmacist reduces the order to writing right away, and the prescriber delivers a written prescription within 7 days marked "Authorization for Emergency Dispensing" with the date of the oral order. There's no 72-hour follow-up and no 30-day allowance.
Source: 21 CFR 1306.11(d)(1), (d)(2), and (d)(4)
Check your state: Look up your state's emergency Schedule II rule.

Question 34 of 50

Area 4: Pharmacy Operations · Select all that apply

Which are factors DEA lists for deciding whether a loss of controlled substances is "significant"? (Select ALL that apply.)

A. The retail price of the drugs
B. The specific controlled substances lost
C. The number of pharmacists on staff
D. The quantity lost compared with the type of business
E. Whether insurance covers the loss

Reveal answer and explanation

Answers: B. The specific controlled substances lost; D. The quantity lost compared with the type of business
DEA's listed factors include the quantity lost relative to the type of business, the specific substances, whether the loss can be tied to particular people or activities, patterns of losses, whether the drugs are likely diversion targets, and local diversion trends. Staffing numbers, price, and insurance aren't factors.
Source: 21 CFR 1301.76(b)(1)–(6)

Question 35 of 50

Jurisdiction-rule drill · Area 1: Licensure/Personnel · Choose one

Jurisdiction rule (assume for this question): Pharmacist licenses expire December 31 of each odd-numbered year. There is no grace period, and practicing on an expired license is unprofessional conduct. On January 3, a pharmacist realizes the license wasn't renewed. May the pharmacist work today?

A. Yes, if the renewal application is submitted today
B. Yes, during a 30-day grace period
C. Yes, if continuing education is complete
D. Yes, if another pharmacist supervises
E. No, not until the license is renewed or reinstated

Reveal answer and explanation

Answer: E. No, not until the license is renewed or reinstated
The license expired on December 31, and the supplied rule allows no grace period. Submitting paperwork, supervision, or completed CE doesn't make an expired license active.
Drill basis: NABP MPJE Competency Statements, Area 1, statement 1.2
Check your state: On your real MPJE, use your board's renewal cycle, grace period (if any), and reinstatement rule.

Question 36 of 50

Area 3: Dispensing Requirements · Choose one

An adult patient's caregiver, who is named in the patient's medical power of attorney, phones the pharmacist and asks that the patient's Schedule II prescription be partially filled. State law doesn't prohibit it. Under federal law, what is the result?

A. Allowed only if the request is made in person
B. Allowed only if the request is notarized
C. Not allowed; only the patient may request a partial fill
D. Allowed, and the pharmacist notes who requested the partial fill and when
E. Not allowed; only the prescriber may request a partial fill

Reveal answer and explanation

Answer: D. Allowed, and the pharmacist notes who requested the partial fill and when
A caregiver named in an adult patient's medical power of attorney may request a partial fill in person, in signed writing, or by phone to the pharmacist. The pharmacist notes who requested it, the request date, and the quantity dispensed. Remaining portions still must be filled within 30 days of the date written.
Source: 21 CFR 1306.13(b)(4) and (b)(5)(ii)

Question 37 of 50

Area 2: Pharmacist Practice · Select all that apply

Under the federal Medicaid counseling standards, which are topics the pharmacist addresses when the pharmacist considers them significant? (Select ALL that apply.)

A. What to do about a missed dose
B. The name and description of the medication
C. The pharmacy's acquisition cost
D. Techniques for self-monitoring drug therapy
E. Proper storage

Reveal answer and explanation

Answers: A. What to do about a missed dose; B. The name and description of the medication; D. Techniques for self-monitoring drug therapy; E. Proper storage
The listed counseling topics are the medication's name and description; dosage form, dose, route, and duration; special directions and precautions; common severe side effects, interactions, and contraindications; self-monitoring; storage; refill information; and missed-dose action. The pharmacy's acquisition cost isn't on the list.
Source: 42 CFR 456.705(c)(3)

Question 38 of 50

Area 4: Pharmacy Operations · Choose one

A pharmacy files its paper Schedule III–V prescriptions in the general numbered prescription file. When does federal law waive the red "C" stamp?

A. When Schedule III–V prescriptions are under 10% of volume
B. When the pharmacy has been open fewer than 5 years
C. Never; the stamp is always required in that file
D. When prescriptions are scanned monthly
E. When the pharmacy's computer system identifies prescriptions by number and retrieves originals by prescriber, patient, drug dispensed, and date filled

Reveal answer and explanation

Answer: E. When the pharmacy's computer system identifies prescriptions by number and retrieves originals by prescriber, patient, drug dispensed, and date filled
Filing paper Schedule III–V prescriptions with noncontrolled prescriptions normally requires a red "C" at least 1 inch high in the lower right corner. The stamp is waived when the pharmacy's computer system can identify prescriptions by number and retrieve the originals by prescriber name, patient name, drug dispensed, and date filled.
Source: 21 CFR 1304.04(h)(4)

Question 39 of 50

Area 2: Pharmacist Practice · Select all that apply

Which are federal conditions for a prescriber to issue multiple Schedule II prescriptions for one patient? (Select ALL that apply.)

A. Issuing multiple prescriptions is permissible under the applicable state law
B. Each prescription after the first shows the earliest date it may be filled
C. Each prescription is issued for a legitimate medical purpose in the usual course of professional practice
D. The prescriber must see the patient every 30 days
E. The combined supply may reach 120 days

Reveal answer and explanation

Answers: A. Issuing multiple prescriptions is permissible under the applicable state law; B. Each prescription after the first shows the earliest date it may be filled; C. Each prescription is issued for a legitimate medical purpose in the usual course of professional practice
The conditions include legitimate medical purpose, written earliest-fill dates, the prescriber's conclusion that the practice doesn't create undue diversion risk, compliance with state law, and a combined total of no more than a 90-day supply. The regulation also says it doesn't require or encourage any particular visit schedule.
Source: 21 CFR 1306.12(b)(1)–(2)

Question 40 of 50

Area 3: Dispensing Requirements · Choose one

A state permits nonprescription sale of Schedule V products. Yesterday afternoon, a 19-year-old bought 120 mL of a Schedule V product that contains opium. Today, the same person asks for 240 mL more of it. What is the most the pharmacist may sell today under federal law?

A. 0 mL
B. 120 mL
C. 240 mL
D. 360 mL
E. 120 mL, and only with a prescription

Reveal answer and explanation

Answer: B. 120 mL
For an opium-containing Schedule V product, no more than 240 mL may be sold to the same purchaser in any 48-hour period. With 120 mL bought yesterday, only 120 mL more is available until the 48 hours pass. At 19, the purchaser meets the 18-and-older requirement. The pharmacist also requires ID if the buyer isn't known and records the sale in a bound record book.
Source: 21 CFR 1306.26(b)–(e)
Check your state: Look up whether your state allows nonprescription Schedule V sales at all.

Question 41 of 50

Jurisdiction-rule drill · Area 1: Licensure/Personnel · Select all that apply

Jurisdiction rule (assume for this question): The board may discipline a licensee for (1) a felony conviction, (2) practicing while impaired, (3) failing to complete required continuing education, or (4) dispensing without a valid prescription. Which conduct is grounds for discipline under this rule? (Select ALL that apply.)

A. Declining to work extra shifts
B. A felony conviction
C. Not completing required continuing education
D. A misdemeanor conviction unrelated to practice
E. Working a shift while impaired

Reveal answer and explanation

Answers: B. A felony conviction; C. Not completing required continuing education; E. Working a shift while impaired
The first three match listed grounds. The rule names felonies, so an unrelated misdemeanor doesn't fit as written, and declining shifts isn't a listed ground. Drills like this reward reading the rule's exact words.
Drill basis: NABP MPJE Competency Statements, Area 1, statement 1.2
Check your state: On your real MPJE, use your state's actual grounds for discipline.

Question 42 of 50

Jurisdiction-rule drill · Area 4: Pharmacy Operations · Choose one

Jurisdiction rule (assume for this question): A pharmacy permit is valid only for the address on the permit. Relocating requires a new permit, issued after the pharmacy passes a board inspection at the new site. A pharmacy moves next week. What must happen before it dispenses at the new address?

A. Notify the board within 30 days after moving
B. Hang the current permit at the new site
C. Nothing; the permit updates automatically
D. Have the PIC sign a relocation affidavit
E. Obtain the new permit, issued after the board inspection

Reveal answer and explanation

Answer: E. Obtain the new permit, issued after the board inspection
Under the supplied rule, the old permit doesn't cover the new address, and the new permit comes only after a passed inspection. Notice after the move or moving the old certificate doesn't satisfy it.
Drill basis: NABP MPJE Competency Statements, Area 4, statement 4.7
Check your state: On your real MPJE, use your state's permit, relocation, and inspection rules.

Question 43 of 50

Jurisdiction-rule drill · Area 2: Pharmacist Practice · Choose one

Jurisdiction rule (assume for this question): When the prescriber can't be reached, a pharmacist may dispense one emergency supply of up to 72 hours of a noncontrolled maintenance medication per prescription and must document it. Which request can be filled under this rule?

A. A 72-hour supply of lisinopril
B. A 30-day supply of lisinopril
C. An emergency supply of a new prescription that was never filled
D. A second emergency supply on the same lisinopril prescription
E. A 72-hour supply of alprazolam

Reveal answer and explanation

Answer: A. A 72-hour supply of lisinopril
Alprazolam is a controlled substance, so the rule's "noncontrolled" limit excludes it. Thirty days exceeds 72 hours, a second supply exceeds "one," and a never-filled new prescription isn't a maintenance refill.
Drill basis: NABP MPJE Competency Statements, Area 2, statement 2.1
Check your state: On your real MPJE, use your state's emergency refill rule, including any quantity and controlled-substance limits.

Question 44 of 50

Area 3: Dispensing Requirements · Choose one

A technician at Pharmacy B calls Pharmacy A to transfer a Schedule III prescription for refills. Pharmacy A's pharmacist is available. Under federal rules, who must communicate the transfer?

A. The technician and Pharmacy A's pharmacist
B. The prescriber
C. The patient
D. Any two licensed employees
E. Two licensed pharmacists, directly

Reveal answer and explanation

Answer: E. Two licensed pharmacists, directly
A transfer of Schedule III–V prescription information for refills must be communicated directly between two licensed pharmacists. A technician can't be one of the two under the federal rule.
Source: 21 CFR 1306.25(b)(1)
Check your state: Look up who your state allows to transfer prescriptions; for controlled substances, the federal pharmacist-to-pharmacist rule also applies.

Question 45 of 50

Jurisdiction-rule drill · Area 1: Licensure/Personnel · Choose one

Jurisdiction rule (assume for this question): A licensee who knows another pharmacist is practicing while impaired must report it to the board, or to the board-approved peer assistance program, within 14 days. You know a colleague has been working impaired. What does the rule require?

A. Report only after a second incident
B. Talk to the colleague and wait to see if it happens again
C. Report to DEA only
D. Report to the board or the board-approved program within 14 days
E. Tell the pharmacy manager only

Reveal answer and explanation

Answer: D. Report to the board or the board-approved program within 14 days
The supplied rule names the recipients (board or approved program) and the deadline (14 days). Telling a manager, waiting, or reporting only to DEA doesn't meet it.
Drill basis: NABP MPJE Competency Statements, Area 1, statement 1.2
Check your state: On your real MPJE, use your state's impairment reporting and peer-assistance rules.

Question 46 of 50

Area 2: Pharmacist Practice · Select all that apply

Which faxed Schedule II prescriptions may serve as the original written prescription under federal law? (Select ALL that apply.)

A. A Schedule II narcotic to be compounded for home intravenous infusion
B. A Schedule II stimulant for an outpatient who lives at home
C. A Schedule II narcotic for a hospice patient, with hospice status noted
D. A Schedule II drug for a resident of a long-term care facility
E. Any Schedule II prescription the prescriber's agent marks "urgent"

Reveal answer and explanation

Answers: A. A Schedule II narcotic to be compounded for home intravenous infusion; C. A Schedule II narcotic for a hospice patient, with hospice status noted; D. A Schedule II drug for a resident of a long-term care facility
Federal rules let the fax serve as the original in three situations: a Schedule II narcotic compounded for direct administration by parenteral, IV, IM, subcutaneous, or intraspinal infusion; a Schedule II drug for an LTCF resident; and a Schedule II narcotic for a hospice patient with hospice status noted. Everyone else needs the original signed prescription before dispensing.
Source: 21 CFR 1306.11(a), (e), (f), and (g)

Question 47 of 50

Area 4: Pharmacy Operations · Choose one

A pharmacy orders hydromorphone tablets, a Schedule II drug, from its wholesaler. What federal ordering document is required?

A. DEA Form 224
B. DEA Form 106
C. DEA Form 41
D. The wholesaler's invoice
E. DEA Form 222 or its electronic equivalent

Reveal answer and explanation

Answer: E. DEA Form 222 or its electronic equivalent
Each distribution of a Schedule I or II controlled substance requires a DEA Form 222 or the electronic equivalent (CSOS orders). Form 106 reports theft or loss, Form 41 documents destruction, and Form 224 is the pharmacy's registration application.
Source: 21 CFR part 1305 (1305.03); DEA Diversion Control Division, DEA Form 222 Q&A (Form 222 requirement)

Question 48 of 50

Area 3: Dispensing Requirements · Select all that apply

Which may be dispensed in non-child-resistant packaging because of a listed federal exemption, with no special request needed? (Select ALL that apply.)

A. Sublingual isosorbide dinitrate 5 mg tablets
B. Oxycodone tablets
C. Sublingual nitroglycerin
D. Cyclically administered oral contraceptives in the manufacturer's mnemonic dispenser package
E. Erythromycin ethylsuccinate granules for oral suspension in a package containing no more than 8 g of erythromycin

Reveal answer and explanation

Answers: A. Sublingual isosorbide dinitrate 5 mg tablets; C. Sublingual nitroglycerin; D. Cyclically administered oral contraceptives in the manufacturer's mnemonic dispenser package; E. Erythromycin ethylsuccinate granules for oral suspension in a package containing no more than 8 g of erythromycin
Oral prescription drugs generally require special (child-resistant) packaging, and the regulation lists specific exemptions, including sublingual nitroglycerin; sublingual and chewable isosorbide dinitrate in strengths of 10 mg or less; erythromycin ethylsuccinate granules in packages of no more than 8 g of erythromycin; and cyclic oral contraceptives in mnemonic packages. Oral controlled substances such as oxycodone are separately listed as requiring special packaging.
Source: 16 CFR 1700.14(a)(4) and (a)(10)

Question 49 of 50

Area 2: Pharmacist Practice · Choose one

A prescriber's agent prepared a Schedule III prescription, and the prescriber signed it. It is missing the patient's address. The pharmacist fills it as written. Who bears responsibility under federal rules for the prescription not meeting DEA requirements?

A. Only the agent who prepared it
B. The prescriber, with a corresponding liability on the pharmacist who filled it
C. Only the pharmacy owner
D. Only the prescriber
E. No one, because Schedule III rules are relaxed

Reveal answer and explanation

Answer: B. The prescriber, with a corresponding liability on the pharmacist who filled it
A secretary or agent may prepare a prescription for the practitioner's signature, but the prescriber is responsible if it doesn't conform to the rules. A corresponding liability rests on the pharmacist who fills a prescription that isn't in the form DEA requires. The patient's address is a required element.
Source: 21 CFR 1306.05(a) and (f)

Question 50 of 50

Jurisdiction-rule drill · Area 1: Licensure/Personnel · Choose one

Jurisdiction rule (assume for this question): Licensure requires 1,500 intern hours, and only hours earned while holding an active intern registration count. A candidate logged 1,600 hours, but 200 were earned before the intern registration was issued. What is the candidate's status?

A. Eligible after passing the NAPLEX
B. Eligible if the preceptor signs off on all 1,600 hours
C. Not yet eligible; 300 more hours are needed
D. Not yet eligible; 1,400 hours count, so 100 more are needed
E. Eligible; 1,600 hours exceeds 1,500

Reveal answer and explanation

Answer: D. Not yet eligible; 1,400 hours count, so 100 more are needed
Only the 1,400 hours earned under an active registration count (1,600 − 200). The requirement is 1,500, so 100 more hours are needed. A preceptor's signature can't count hours the rule excludes.
Drill basis: NABP MPJE Competency Statements, Area 1, statement 1.2
Check your state: On your real MPJE, use your board's internship hour and registration rules.

Answer key and self-scoring

Score one point per question. A select-all question counts only when you picked every correct choice and nothing else. That's our scoring rule for this set; select-all questions here can have two, three, or four correct choices.

Answer key and self-scoring
#	Area	Format	Answer
1	3	One answer	B
2	2	One answer	A
3	4	One answer	B
4	1	One answer	A
5	2	One answer	D
6	3	Select all	A, B, C
7	4	One answer	A
8	1	One answer	C
9	2	Select all	A, B, C, E
10	3	One answer	A
11	4	Select all	D, E
12	2	One answer	B
13	1	One answer	E
14	3	One answer	B
15	2	One answer	C
16	4	One answer	A
17	1	One answer	C
18	2	One answer	D
19	3	One answer	D
20	4	One answer	B
21	2	One answer	C
22	1	Select all	B, C, D
23	3	Select all	A, B, D
24	2	One answer	D
25	4	Select all	A, B, D
26	1	One answer	C
27	3	One answer	C
28	2	One answer	C
29	4	One answer	B
30	2	One answer	E
31	1	One answer	A
32	3	Select all	A, B, E
33	2	Select all	A, C, D
34	4	Select all	B, D
35	1	One answer	E
36	3	One answer	D
37	2	Select all	A, B, D, E
38	4	One answer	E
39	2	Select all	A, B, C
40	3	One answer	B
41	1	Select all	B, C, E
42	4	One answer	E
43	2	One answer	A
44	3	One answer	E
45	1	One answer	D
46	2	Select all	A, C, D
47	4	One answer	E
48	3	Select all	A, C, D, E
49	2	One answer	B
50	1	One answer	D

Score by area. Add up your points in each group:

Answer key and self-scoring
Area	Questions	Your score
1: Licensure/Personnel	4, 8, 13, 17, 22, 26, 31, 35, 41, 45, 50	___ / 11
2: Pharmacist Practice	2, 5, 9, 12, 15, 18, 21, 24, 28, 30, 33, 37, 39, 43, 46, 49	___ / 16
3: Dispensing Requirements	1, 6, 10, 14, 19, 23, 27, 32, 36, 40, 44, 48	___ / 12
4: Pharmacy Operations	3, 7, 11, 16, 20, 25, 29, 34, 38, 42, 47	___ / 11

The area counts (11, 16, 12, 11) roughly follow NABP's current weights of 22%, 33%, 24%, and 21%. That's our allocation for a 50-question set, not an NABP form.

What your score means

It's your score on these 50 questions. It isn't an MPJE score, and it doesn't predict whether you'll pass. NABP reports the real MPJE only as pass or fail, with no score to compare against, and 11 to 16 questions per area is far too few to measure an area precisely.

Use the area totals to decide what to open first, not to decide whether you're ready. A weak area here is a lead worth checking against your own state's rules.

What your misses are telling you

A miss here can come from three places: not knowing the federal rule, not knowing where your state changes it, or misreading what the question actually asked. The table sorts the rules in this set by where the federal regulation itself hands the decision to your state, so you know exactly what to look up next.

What your misses are telling you
If you missed…	The federal rule in one line	Where your state can change the answer	Look up in your state's rules
Schedule II partial fills (questions 1, 19, 32, 36)	Patient-requested partials: remainder within 30 days of the written date; pharmacy-short: 72 hours; LTCF or terminally ill: up to 60 days	Patient-requested partials are allowed only if state law doesn't prohibit them (1306.13(b)(1)(i))	Whether your state allows or limits them
Multiple Schedule II prescriptions (questions 2, 39)	Up to a combined 90-day supply, earliest fill date on each after the first	Must be permissible under state law (1306.12(b)(1)(iv))	Whether your state allows them; any day-supply limit
Electronic prescription transfers (question 27)	One-time transfer for initial filling, in electronic form	Only if state law allows it (1306.08(g))	Whether your state permits it
Refill transfers (questions 10, 44)	One-time only unless the pharmacies share a real-time database; pharmacist to pharmacist	Your state may add limits	Your state's transfer rule
Storage and security (question 25)	Locked cabinet or dispersal through stock	Your state may restrict dispersal	Your state's storage rule
Records and inventory (questions 11, 16, 20, 29, 38)	Keep records at least 2 years; biennial inventory	"At least" is a floor; your state may require longer retention or more frequent inventories	Your retention period and inventory schedule
Nonprescription Schedule V and pseudoephedrine (questions 13, 14, 31, 40)	Pharmacist-only Schedule V sale with quantity, age, ID, and record-book rules; 3.6 g pseudoephedrine base per day	Your state may prohibit nonprescription Schedule V sales or set lower pseudoephedrine limits	Whether your state allows either, and its limits
Counseling and drug review (questions 21, 23, 28, 37)	Medicaid rules require state counseling standards and prospective review	The state writes the counseling standards (42 CFR 456.705)	New vs. refill, who may make the offer, documentation, PDMP checks
Any jurisdiction-rule drill (questions 8, 12, 17, 26, 30, 35, 41, 42, 43, 45, 50)	None; these topics are almost all state law	Entirely	Your board's rules on technician ratios, CE, PIC changes, renewals, discipline, internships, immunizations, returns, emergency refills, and permits

If you missed a question you "knew," that's usually a reading problem, not a knowledge problem. Look for the qualifier you skipped: noncontrolled, per calendar day, second renewal, written date versus first fill date.

How to review a missed question

Open the source, not just the explanation. Every answer above links to the regulation that settles it. Read the paragraph.
Write the rule in one sentence, including its exception and its time or quantity limit.
Add your state's version beside it. If your state is stricter or adds a condition, write that down with the rule number. This is the part a federal practice set can't do for you.
Change one fact and answer again. If the rule is 72 hours for a pharmacy-short partial, ask what changes when the patient requested it. If your answer doesn't change when it should, you memorized the answer instead of the rule.
Retry your misses without looking a day or two later.

The MPJE hub has a downloadable state-law source matrix if you want a ready-made place to record federal and state rules side by side.

Why these answers use federal law, but your MPJE won't

NABP says the MPJE makes no distinction between federal and state questions: you answer each one under the prevailing law of the state where you're seeking licensure. There's a separate MPJE for each jurisdiction.

A free test that works for every state can't honestly pretend to know each state's law. So this set does two things instead. The federal questions teach the layer every state sits on, each marked "assume no stricter state rule applies" or giving the state condition in the question. The drills give you a made-up state rule and test whether you apply it exactly. On test day, if your state's rule is different from a federal answer here, your state's answer is the one that counts.

Be careful with the shortcut "always pick the stricter rule." NABP's instruction is to apply your state's prevailing law, not to pick whichever rule looks stricter, and a question can turn on a state rule that isn't simply stricter or looser. Learn the actual state rule.

Are you taking the MPJE at all?

Check before you study. The state-specific MPJE isn't the law exam everywhere.

Your own board's exam: Arkansas, California, Nevada, and Puerto Rico run their own jurisprudence exams.
No jurisprudence exam for initial licensure: Alaska, Idaho, Indiana, Michigan, New Hampshire, Vermont, and the Virgin Islands.
Moving to the Uniform MPJE (UMPJE): 13 jurisdictions are on NABP's transition table.

Source: NABP, Which states require the MPJE or UMPJE? and UMPJE participating states.

Are you taking the MPJE at all?
Jurisdiction	UMPJE start	State-specific MPJE retirement date
Arizona	April 1, 2026	March 31, 2026
Florida	June 1, 2026	May 31, 2026
Iowa	April 1, 2026	March 31, 2026
Kansas	April 1, 2026	March 31, 2027
Maryland	June 1, 2026	May 31, 2027
Montana	June 1, 2026	May 31, 2026
Nebraska	June 1, 2026	May 31, 2028
North Carolina	April 1, 2026	March 31, 2026
Ohio	April 1, 2026	September 30, 2026
Rhode Island	April 1, 2026	March 31, 2026
Virginia	September 1, 2026	September 30, 2026
Washington	July 2, 2026	December 29, 2026
West Virginia	June 1, 2026	August 1, 2026

NABP cancels, with a full refund, any MPJE appointment scheduled on or after a state's retirement date. If you already passed that state's MPJE on or before the transition date, NABP says you don't also need the UMPJE. Where the dates overlap, don't assume you get to choose: the exam named on your Authorization to Test and your board decide. To match your state and test date to an exam and blueprint, use the MPJE and UMPJE route checker.

How this set compares with the real MPJE

How this set compares with the real MPJE
Row label	Real MPJE	This practice set
Questions	120, with 100 scored and 20 unscored pretest questions	50, all counted
Time	2.5 hours	No limit; about 62.5 minutes at the real exam's pace (150 ÷ 120 = 75 seconds per question)
Question order	Adaptive; answered in order, no skipping, no going back	Fixed order; you can go back
Formats	One-answer and select-all in NABP's current sample file	One-answer and select-all
Law tested	Your state's law and federal law, with no labels	Federal law, plus drills with a supplied state rule
Result	Pass or fail	Your count out of 50

Sources: NABP Candidate Application Bulletin, Section 4; NABP Take the MPJE; NABP current sample questions. An earlier NABP sample file also showed an ordered-response (drag into order) format, and NABP's current file says question types may be added or removed. The testing-center tutorial shows every format before you start.

To practice the no-going-back rule, answer each question once, commit, and don't reopen it until you've finished all 50.

Which blueprint applies to your test date?

Which blueprint applies to your test date?
Test date	Blueprint	Areas or domains
Before March 1, 2027	MPJE Competency Statements	Licensure/Personnel 22%, Pharmacist Practice 33%, Dispensing Requirements 24%, Pharmacy Operations 21%
On or after March 1, 2027	MPJE Content Outline	Pharmacy and Pharmacist Practice 30%, Medication Use Process 30%, Regulatory Authority and Legal Obligations 20%, Pharmacy Operations 20%

This set is tagged to the current Competency Statements. The March 1, 2027 blueprint switch does not itself change the federal rules tested here; it changes how NABP organizes the content. NABP announced the new outline on June 10, 2026, with an effective date of March 1, 2027. For how current topics move into the new domains, see the MPJE hub's 2027 crosswalk.

Should you also take the official Pre-MPJE?

NABP's Pre-MPJE is the official practice exam: 40 state-specific questions in 50 minutes, $90 per attempt, once a year per jurisdiction, taken within 7 days of purchase. NABP says it draws on the only official MPJE question bank of past questions. It reports a total scaled score, which the real MPJE does not, so don't read that number as a pass prediction. NABP prohibits using AI tools at any point during it.

The two do different jobs. Use this free set as often as you like to learn and check federal rules against their sources. Use the Pre-MPJE when you want NABP's own state-specific questions and format, and decide in advance whether you're spending your one attempt early to find gaps or late as a dress rehearsal. NABP suggests taking it early.

Questions people ask about MPJE practice

Are these real MPJE questions? No. Castleport wrote all 50. None are recalled, copied, or rebuilt from NABP material.

Is this enough to pass my state's MPJE? No single resource is, and this one covers the federal layer and the skill of applying a supplied state rule. You still need your own board's statutes and rules.

What score here means I'm ready? There isn't one. This set has no pass line, and the real exam reports only pass or fail.

I'm taking the UMPJE. Is this useful? The federal rules overlap, but the UMPJE is a different exam with its own outline. Start with the UMPJE practice questions.

Fees, retakes, attempt limits, results timing? Those live on the MPJE and UMPJE exam hub, with NABP's official sources.

Sources

Federal regulations were rechecked in the eCFR on September 25, 2026; the cited eCFR pages displayed currency dates from September 21 through September 23, 2026. The other official sources below were also rechecked on September 25, 2026.

NABP

MPJE Competency Statements (page updated June 1, 2026)
Candidate Application Bulletin, Section 4: What Is the MPJE? (June 2026)
Take the MPJE
MPJE sample questions (current) and earlier sample file
MPJE Content Outline, effective March 1, 2027 and NABP announcement
Which states require the MPJE or UMPJE? (page updated September 11, 2026)
UMPJE participating states (page updated August 26, 2026)
Pre-MPJE and Pre-UMPJE

DEA regulations and guidance (21 CFR)

FDA, CPSC, and CMS

Castleport's methodology and corrections log explain how we check and fix what we publish.

Written by the Castleport Test Prep Editorial Team · Last verified: September 25, 2026 (federal regulations and NABP pages listed above)

Castleport Test Prep is an independent exam prep publisher. It is not affiliated with, endorsed by, or approved by the National Association of Boards of Pharmacy (NABP) or any board of pharmacy. MPJE, UMPJE, and other exam names are used only to identify the exams discussed; trademarks belong to their respective owners. All 50 questions are original, unofficial practice items. This page is study material, not legal advice; confirm requirements with your board of pharmacy.